| 角色 |
演员 |
配音 |
备注 |
| 托尼·斯塔克/钢铁侠 | 小罗伯特·唐尼 | | |
| 史蒂夫·罗杰斯/美国队长 | 克里斯·埃文斯 | | |
| 雷神 | 克里斯·海姆斯沃斯 | | |
| 灭霸 | 乔什·布洛林 | | |
| 绿巨人 | 马克·鲁法洛 | | |
| 奇异博士 | 本尼迪克特·康伯巴奇 | | |
| 彼得·帕克/蜘蛛侠 | 汤姆·赫兰德 | | |
| 娜塔莎·罗曼诺夫/黑寡妇 | 斯嘉丽·约翰逊 | | |
| 黑豹 | 查德维克·博斯曼 | | |
| 巴基·巴恩斯/冬兵 | 塞巴斯蒂安·斯坦 | | |
| 旺达·马克西莫夫/红女巫 | 伊丽莎白·奥尔森 | | |
| 幻视 | 保罗·贝坦尼 | | |
| 星爵 | 克里斯·帕拉特 | | |
| 卡魔拉 | 佐伊·索尔达娜 | | |
| 火箭 | 布莱德利·库珀 | | |
| 格鲁特 | 范·迪塞尔 | | |
| 德拉克斯 | 戴夫·巴蒂斯塔 | | |
| 星云 | 凯伦·吉兰 | | |
| 螳螂女 | 庞·克莱门捷夫 | | |
| 洛基 | 汤姆·希德勒斯顿 | | |
| 猎鹰 | 安东尼·麦凯 | | |
| 战争机器 | 唐·钱德尔 | | |
| 王 | 本尼迪特·王 | | |
| 苏睿公主 | 莱蒂希娅·赖特 | | |
| 奥科耶 | 达娜·古瑞拉 | | |
| 矮人王艾崔 | 彼特·丁拉基 | | |
| 收藏者 | 本尼西奥·德尔·托罗 | | |
| 幼年卡魔拉 | 阿丽亚娜·格林布拉特 | | |
| 阿尤 | 弗洛伦斯·卡萨姆巴 | | |
| 尼克·弗瑞 | 塞缪尔·杰克逊 | | |
| 火箭浣熊（动作捕捉） | 西恩·古恩 | | |
| 格鲁特（动作捕捉） | 泰瑞·诺塔里 | | |
| 小辣椒 | 格温妮丝·帕特洛 | | |
| 人猿姆巴库 | 温斯顿·杜克 | | |
| AI秘书"周五" | 凯瑞·康顿 | | |
| 海姆达尔 | 伊德瑞斯·艾尔巴 | | |
| 乌木喉 | 汤姆·沃恩-劳勒 | | |
| 暗夜比邻星 | 凯丽·库恩 | | |
| 亡刃将军 | 迈克尔·詹姆斯·肖 | | |
| 国务卿 | 威廉·赫特 | | |
| 校车司机 | 斯坦·李 | | |
| 特工希尔 | 寇碧·史莫德斯 | | |
| 奈德 | 雅各·巴塔伦 | | |
| 红骷髅 | 罗斯·马昆德 | | |
| JackRollins(uncredited) | 卡兰·穆尔韦 | | |
| Sally | IsabellaAmara | | |
| Mourner(uncredited) | LucieCarroll | | |
| NYCPedestrian(uncredited) | JamesSterling | | |
| NYCPedestrian(uncredited) | JamesSiderits | | |
| TaxiCabDriver(uncredited) | DavidDmanEscobar | | |
| Cindy | TiffanyEspensen | | |
| Asgardian(uncredited) | MatthewExcelSimm.. | | |
| Pedestrian(uncredited) | AnniePisapia | | |
| NYCMaintenance(uncredited) | MichaelYuhl | | |
| DrillSergeant(uncredited) | BrentGaskins | | |
| Constructionworker(uncredited) | EdwardParker | | |
| Merchant(uncredited) | JamelChambers | | |
| NewYorkPedestrian(uncredited) | ChristinaWebling | | |
| ConstructionWorker(uncredited) | MartaviousGrayles | | |
| Asgardian(uncredited) | SlimKhezri | | |
| NYPD(uncredited) | JohnGettier | | |
| NYPD(uncredited) | SergioBriones | | |
| NationalGuard(uncredited) | DanielaGaskie | | |
| NYCPedestrian(uncredited) | TonyDupar | | |
| NYCPedestrian(uncredited) | DevinKoehler | | |
| Asgardian(uncredited) | DemetriLandell | | |
| NYCPedestrian/Phil(uncredited) | JohnSchier | | |
| BusinessWorker(uncredited) | PerlaMiddleton | | |
| StreetPedestrian#2 | MatthewZuk | | |
| JabariWarrior(uncredited) | FloydAnthonyJohn.. | | |
| NYCPedestrian(uncredited) | JacobEvans | | |
| StreetPedestrian#1 | BlairJasin | | |
| Tiny | EthanDizon | | |
| WoundedBusinessMan(uncredited) | MichaelPierinoMi.. | | |
| NYCPedestrian(uncredited) | ChaseLedgerwood | | |
| Citizen(uncredited) | KejuanLondonKeith | | |
| NYCPedestrian(uncredited) | MalloryKidwell | | |
| Student(uncredited) | MatthewChristensen | | |
| Soldier(uncredited) | StevenEssani | | |
| Student(uncredited) | KevinMontgomery | | |
| On-SetProximaMidnight | 莫妮卡·甘德顿 | | |
| Gamora'sMother | AmeenahKaplan | | |
| SecretaryRoss'Aide | MichaelAnthonyRo.. | | |
| SecretaryRoss'Aide | 斯蒂芬·麦克菲利 | | |
| DoctorStrangeDouble | AaronLazar | | |
| ThanosReader | 罗伯特·普拉格 | | |
| TeenageGrootReader | OlaniyanThurmon | | |
| ScottishNews(STV)Reporter | LauraMiller | | |
| DoraMilaje(uncredited) | MarijaJulietteAb.. | | |
| CoffeeShopEmployee(uncredited) | 所罗门·格雷夫 | | |
| Zen-WhoberiElder(uncredited) | EmelitaT.Gonzalez | | |
| PatroninVehicle(uncredited) | CecilM.Henry | | |
| MedicalAssistant(uncredited) | LukeMaher | | |
| NYCPedestrian(uncredited) | JaredMoser | | |
| DoraMilaje(uncredited) | MarieMouroum | | |
| BoyonBus(uncredited) | HarrisonOsterfield | | |
| NYCPedestrian(uncredited) | ShawnSouth | | |
| NewYorkPedestrian(uncredited) | TravisThompson | | |
